In vivo injectable gels for tissue repair
Identifieur interne : 004738 ( Main/Exploration ); précédent : 004737; suivant : 004739In vivo injectable gels for tissue repair
Auteurs : Jons Hilborn [Suède]Source :
- Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology [ 1939-5116 ] ; 2011-11.
Descripteurs français
- Wicri :
- topic : Biomatériau, Conférence internationale, Polymère.
English descriptors
- KwdEn :
- Adhesion, Alginate, Amino acid sequence, Animal models, Annual meeting, Appl biomater, Augmentation rhinoplasty, Bioactive, Bioactive molecules, Biological activity, Biological outcome, Biological properties, Biomaterials, Biomed, Biomed mater, Block copolymers, Bone formation, Bone regeneration, Bone tissue engineering, Bovine chondrocytes, Brin, Brotic transformation, Burst release, Cartilage, Cartilage regeneration, Cell adhesion, Cell carrier, Cell survival, Cell viability, Cells cocultured, Chitosan, Chondrocytes, Chondroitin sulfate, Collagen, Compressive modulus, Compressive strength, Copolymer, Covalent crosslinking, Crosslinked, Crosslinked hyaluronan, Crosslinking, Degradation, Delivery system, Design freedom, Drug deliv, Drug delivery, Elastin, Encapsulated, Fibrin, Functional evaluation, Functional tissue, Gelatin, Gelation, Gelation rate, Healthcare costs, Heparin, Horseradish peroxidase, Hyaluronan, Hydrogel, Immune response, Implant, Important role, Injectable, Injectable biomaterial, Injectable materials, Injectable nanomaterials, Injectable scaffolds, International conference, Invasive, Invasive methods, Macromol biosci, Mater, Material characteristics, Matrix, Mechanical loading, Mechanical properties, Mechanical strength, Msc, Nano lett, Nanobiotechnology, Nanomedicine, Network structure, Nucleous, Nucleus pulposus cells, Peptide, Peptide scaffold, Physiological conditions, Polymer, Proteolytic degradation, Pulposa, Pure polymer, Receptor, Regeneration, Regenerative medicine, Release rate, Scaffold, Slower release, Soft matter, Soft tissue, Subcutaneous injection, Such procedures, Surg, Synthetic materials, Tissue engineering, Tissue engineering applications, Tissue engineering scaffolds, Tissue regeneration, Triblock copolymer, Various treatments, Vivo, Vivo injectable, Vivo studies, Wiley, Wires nanomedicine.
- Teeft :
- Adhesion, Alginate, Amino acid sequence, Animal models, Annual meeting, Appl biomater, Augmentation rhinoplasty, Bioactive, Bioactive molecules, Biological activity, Biological outcome, Biological properties, Biomaterials, Biomed, Biomed mater, Block copolymers, Bone formation, Bone regeneration, Bone tissue engineering, Bovine chondrocytes, Brin, Brotic transformation, Burst release, Cartilage, Cartilage regeneration, Cell adhesion, Cell carrier, Cell survival, Cell viability, Cells cocultured, Chitosan, Chondrocytes, Chondroitin sulfate, Collagen, Compressive modulus, Compressive strength, Copolymer, Covalent crosslinking, Crosslinked, Crosslinked hyaluronan, Crosslinking, Degradation, Delivery system, Design freedom, Drug deliv, Drug delivery, Elastin, Encapsulated, Fibrin, Functional evaluation, Functional tissue, Gelatin, Gelation, Gelation rate, Healthcare costs, Heparin, Horseradish peroxidase, Hyaluronan, Hydrogel, Immune response, Implant, Important role, Injectable, Injectable biomaterial, Injectable materials, Injectable nanomaterials, Injectable scaffolds, International conference, Invasive, Invasive methods, Macromol biosci, Mater, Material characteristics, Matrix, Mechanical loading, Mechanical properties, Mechanical strength, Msc, Nano lett, Nanobiotechnology, Nanomedicine, Network structure, Nucleous, Nucleus pulposus cells, Peptide, Peptide scaffold, Physiological conditions, Polymer, Proteolytic degradation, Pulposa, Pure polymer, Receptor, Regeneration, Regenerative medicine, Release rate, Scaffold, Slower release, Soft matter, Soft tissue, Subcutaneous injection, Such procedures, Surg, Synthetic materials, Tissue engineering, Tissue engineering applications, Tissue engineering scaffolds, Tissue regeneration, Triblock copolymer, Various treatments, Vivo, Vivo injectable, Vivo studies, Wiley, Wires nanomedicine.
Abstract
The desire to reduce healthcare costs while improving outcomes drives minimally invasive methods to replacing traditional surgical procedures. Various treatments that would previously have needed open‐type surgeries can be carried out using endoscopes, catheters, and needles. These advantages have become especially obvious for tissue engineering and regenerative medicine with in vivo gel injectable nanomaterials. In this review, the state of the art in this rapidly developing field is given. This is done by contrasting functional evaluation in vitro with in vivo followed by describing (1) synthetic materials, (2) the body's own polymers, (3) polymers in nature, (4) self‐assembled peptides, and (5) new innovations and combinations. With increased understanding of the relationship between material characteristics and the outcome in vivo more rational design criteria are emerging . WIREs Nanomed Nanobiotechnol 2011 3 589–606 DOI: 10.1002/wnan.91 For further resources related to this article, please visit the WIREs website.
Url:
DOI: 10.1002/wnan.91
Affiliations:
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Le document en format XML
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<term>Annual meeting</term>
<term>Appl biomater</term>
<term>Augmentation rhinoplasty</term>
<term>Bioactive</term>
<term>Bioactive molecules</term>
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<term>Biological properties</term>
<term>Biomaterials</term>
<term>Biomed</term>
<term>Biomed mater</term>
<term>Block copolymers</term>
<term>Bone formation</term>
<term>Bone regeneration</term>
<term>Bone tissue engineering</term>
<term>Bovine chondrocytes</term>
<term>Brin</term>
<term>Brotic transformation</term>
<term>Burst release</term>
<term>Cartilage</term>
<term>Cartilage regeneration</term>
<term>Cell adhesion</term>
<term>Cell carrier</term>
<term>Cell survival</term>
<term>Cell viability</term>
<term>Cells cocultured</term>
<term>Chitosan</term>
<term>Chondrocytes</term>
<term>Chondroitin sulfate</term>
<term>Collagen</term>
<term>Compressive modulus</term>
<term>Compressive strength</term>
<term>Copolymer</term>
<term>Covalent crosslinking</term>
<term>Crosslinked</term>
<term>Crosslinked hyaluronan</term>
<term>Crosslinking</term>
<term>Degradation</term>
<term>Delivery system</term>
<term>Design freedom</term>
<term>Drug deliv</term>
<term>Drug delivery</term>
<term>Elastin</term>
<term>Encapsulated</term>
<term>Fibrin</term>
<term>Functional evaluation</term>
<term>Functional tissue</term>
<term>Gelatin</term>
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<term>Heparin</term>
<term>Horseradish peroxidase</term>
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<term>Important role</term>
<term>Injectable</term>
<term>Injectable biomaterial</term>
<term>Injectable materials</term>
<term>Injectable nanomaterials</term>
<term>Injectable scaffolds</term>
<term>International conference</term>
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<term>Invasive methods</term>
<term>Macromol biosci</term>
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<term>Matrix</term>
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<term>Mechanical strength</term>
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<term>Nano lett</term>
<term>Nanobiotechnology</term>
<term>Nanomedicine</term>
<term>Network structure</term>
<term>Nucleous</term>
<term>Nucleus pulposus cells</term>
<term>Peptide</term>
<term>Peptide scaffold</term>
<term>Physiological conditions</term>
<term>Polymer</term>
<term>Proteolytic degradation</term>
<term>Pulposa</term>
<term>Pure polymer</term>
<term>Receptor</term>
<term>Regeneration</term>
<term>Regenerative medicine</term>
<term>Release rate</term>
<term>Scaffold</term>
<term>Slower release</term>
<term>Soft matter</term>
<term>Soft tissue</term>
<term>Subcutaneous injection</term>
<term>Such procedures</term>
<term>Surg</term>
<term>Synthetic materials</term>
<term>Tissue engineering</term>
<term>Tissue engineering applications</term>
<term>Tissue engineering scaffolds</term>
<term>Tissue regeneration</term>
<term>Triblock copolymer</term>
<term>Various treatments</term>
<term>Vivo</term>
<term>Vivo injectable</term>
<term>Vivo studies</term>
<term>Wiley</term>
<term>Wires nanomedicine</term>
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<term>Alginate</term>
<term>Amino acid sequence</term>
<term>Animal models</term>
<term>Annual meeting</term>
<term>Appl biomater</term>
<term>Augmentation rhinoplasty</term>
<term>Bioactive</term>
<term>Bioactive molecules</term>
<term>Biological activity</term>
<term>Biological outcome</term>
<term>Biological properties</term>
<term>Biomaterials</term>
<term>Biomed</term>
<term>Biomed mater</term>
<term>Block copolymers</term>
<term>Bone formation</term>
<term>Bone regeneration</term>
<term>Bone tissue engineering</term>
<term>Bovine chondrocytes</term>
<term>Brin</term>
<term>Brotic transformation</term>
<term>Burst release</term>
<term>Cartilage</term>
<term>Cartilage regeneration</term>
<term>Cell adhesion</term>
<term>Cell carrier</term>
<term>Cell survival</term>
<term>Cell viability</term>
<term>Cells cocultured</term>
<term>Chitosan</term>
<term>Chondrocytes</term>
<term>Chondroitin sulfate</term>
<term>Collagen</term>
<term>Compressive modulus</term>
<term>Compressive strength</term>
<term>Copolymer</term>
<term>Covalent crosslinking</term>
<term>Crosslinked</term>
<term>Crosslinked hyaluronan</term>
<term>Crosslinking</term>
<term>Degradation</term>
<term>Delivery system</term>
<term>Design freedom</term>
<term>Drug deliv</term>
<term>Drug delivery</term>
<term>Elastin</term>
<term>Encapsulated</term>
<term>Fibrin</term>
<term>Functional evaluation</term>
<term>Functional tissue</term>
<term>Gelatin</term>
<term>Gelation</term>
<term>Gelation rate</term>
<term>Healthcare costs</term>
<term>Heparin</term>
<term>Horseradish peroxidase</term>
<term>Hyaluronan</term>
<term>Hydrogel</term>
<term>Immune response</term>
<term>Implant</term>
<term>Important role</term>
<term>Injectable</term>
<term>Injectable biomaterial</term>
<term>Injectable materials</term>
<term>Injectable nanomaterials</term>
<term>Injectable scaffolds</term>
<term>International conference</term>
<term>Invasive</term>
<term>Invasive methods</term>
<term>Macromol biosci</term>
<term>Mater</term>
<term>Material characteristics</term>
<term>Matrix</term>
<term>Mechanical loading</term>
<term>Mechanical properties</term>
<term>Mechanical strength</term>
<term>Msc</term>
<term>Nano lett</term>
<term>Nanobiotechnology</term>
<term>Nanomedicine</term>
<term>Network structure</term>
<term>Nucleous</term>
<term>Nucleus pulposus cells</term>
<term>Peptide</term>
<term>Peptide scaffold</term>
<term>Physiological conditions</term>
<term>Polymer</term>
<term>Proteolytic degradation</term>
<term>Pulposa</term>
<term>Pure polymer</term>
<term>Receptor</term>
<term>Regeneration</term>
<term>Regenerative medicine</term>
<term>Release rate</term>
<term>Scaffold</term>
<term>Slower release</term>
<term>Soft matter</term>
<term>Soft tissue</term>
<term>Subcutaneous injection</term>
<term>Such procedures</term>
<term>Surg</term>
<term>Synthetic materials</term>
<term>Tissue engineering</term>
<term>Tissue engineering applications</term>
<term>Tissue engineering scaffolds</term>
<term>Tissue regeneration</term>
<term>Triblock copolymer</term>
<term>Various treatments</term>
<term>Vivo</term>
<term>Vivo injectable</term>
<term>Vivo studies</term>
<term>Wiley</term>
<term>Wires nanomedicine</term>
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<front><div type="abstract" xml:lang="en">The desire to reduce healthcare costs while improving outcomes drives minimally invasive methods to replacing traditional surgical procedures. Various treatments that would previously have needed open‐type surgeries can be carried out using endoscopes, catheters, and needles. These advantages have become especially obvious for tissue engineering and regenerative medicine with in vivo gel injectable nanomaterials. In this review, the state of the art in this rapidly developing field is given. This is done by contrasting functional evaluation in vitro with in vivo followed by describing (1) synthetic materials, (2) the body's own polymers, (3) polymers in nature, (4) self‐assembled peptides, and (5) new innovations and combinations. With increased understanding of the relationship between material characteristics and the outcome in vivo more rational design criteria are emerging . WIREs Nanomed Nanobiotechnol 2011 3 589–606 DOI: 10.1002/wnan.91 For further resources related to this article, please visit the WIREs website.</div>
</front>
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